 
 body {
    font-family: "Google Sans", sans-serif;
    font-optical-sizing: auto;
    font-size: 0.95rem;
    font-weight: normal;
    font-style: normal;
    font-variation-settings: "GRAD" 0;
    background: #f9faff;
}
 a, button {
     transition: .3s all ease;
     color: #8e5ce1;
     text-decoration: none;
}
 a:hover, a:focus, button:hover, button:focus {
     text-decoration: none;
     color: #9427d8;
     outline: none !important;
     box-shadow: none !important;
}
 h1, h2, h3, h4, h5, h6 {
     line-height: 1.5;
     color: rgba(0, 0, 0, 0.8);
     font-weight: 400;
}
/* Navbar theme */
 .ppgx-navbar-light {
     background: #ffffff !important;
     box-shadow: rgba(0, 0, 0, 0.04) 0px 3px 5px;
     position: absolute;
     left: 0;
     right: 0;
     z-index: 3;
     padding: 0;
}
 @media (max-width: 991.98px) {
     .ppgx-navbar-light {
         background: #481e8f !important;
         padding: 1em 0;
         position: relative;
         top: 0;
    }
}
 .ppgx-navbar-light .navbar-brand {
     color: #000000;
     padding: 0;
     position: relative;
     z-index: 0;
}
 .ppgx-navbar-light .navbar-brand small {
     color: #8a48fa;
}
 @media (max-width: 991.98px) {
     .ppgx-navbar-light .navbar-brand {
         color: #986ce2;
    }
     .ppgx-navbar-light .navbar-nav {
         padding-top: 20px;
    }
 .ppgx-navbar-light .navbar-brand small {
     color: #fff;
}
}
 .ppgx-navbar-light .navbar-nav > .nav-item > .nav-link {
     font-size: 15px;
     padding-top: 1.7rem;
     padding-bottom: 1.7rem;
     padding-left: 25px;
     padding-right: 25px;
     color: rgba(0, 0, 0, 0.8);
     font-weight: 400;
}
 @media (max-width: 991.98px) {
     .ppgx-navbar-light .navbar-nav > .nav-item > .nav-link {
         padding-left: 10px;
         padding-right: 10px;
         padding-bottom: 1rem;
         padding-top: 0;
         color: #fff;
    }
}
 .ppgx-navbar-light .navbar-nav > .nav-item > .nav-link.active {
     color: #8f4ff9;
}
 @media (max-width: 991.98px) {
     .ppgx-navbar-light .navbar-nav > .nav-item > .nav-link.active {
         color: #fff !important;
    }
}
 @media (min-width: 991px) {
    .nav-link:hover {
      background-color: #eee;
    }
}
 .ppgx-navbar-light .navbar-toggler {
     border: none;
     color: rgba(255, 255, 255, 0.9) !important;
     cursor: pointer;
     padding-right: 0;
     font-size: 16px;
     letter-spacing: .1em;
}
/* Brand styling */
 .navbar-brand {
     font-weight: 800;
     font-size: 27px;
     color: #8f4ff9;
     z-index: 3;
     position: relative;
     line-height: 1.1;
}
 .navbar-brand small {
     font-size: 27px;
}
 .navbar-brand span {
     color: #a6a6a6;
     line-height: 1.1;
     text-transform: uppercase;
     font-size: 11px;
     display: block;
     font-weight: 500;
     letter-spacing: 1px;
}
/* Sections */
 .ppgx-section {
    padding-left: 2em;
    padding-right: 2em;
     padding-top: 5em;
     padding-bottom: 3em;
     position: relative;
     width: 100%;
     overflow-x: hidden;
}
.ppgx-section p {
     text-align: justify;
     line-height: 1.8;
}

 @media (max-width: 575.98px) {
     .ppgx-section {
         padding: 6em 0;
    }
}
/* Heading block */
 .heading-section .subheading {
     font-size: 13px;
     display: block;
     margin-bottom: 5px;
     color: rgba(0, 0, 0, 0.3);
     font-weight: 600;
     text-transform: uppercase;
     letter-spacing: 1px;
}
 .heading-section h2 {
     font-size: 38px;
     font-weight: 500;
     line-height: 1.4;
}
 @media (max-width: 991.98px) {
     .heading-section h2 {
         font-size: 40px;
    }
}

/* Theme buttons */
 .btn {
     padding: 9px 12px;
     cursor: pointer;
     border-radius: 4px;
     box-shadow: 0px 24px 36px -11px rgba(0, 0, 0, 0.09);
     font-size: 13px;
     font-weight: 600;
     text-transform: uppercase;
     letter-spacing: 1px;
}
 .btn.btn-primary {
     background: #8f4ff9 !important;
     border: 1px solid #8f4ff9 !important;
     color: #fff !important;
}
 .btn.btn-primary:hover {
     border: 1px solid #8f4ff9;
     background: transparent;
     color: #8f4ff9;
}
/* Services cards */
 .services-wrap {
     position: relative;
     margin-bottom: 25px;
}
 .services-wrap .services {
     padding: 40px;
     display: block;
     width: 100%;
     margin-bottom: 0px;
     border-radius: 5px;
     box-shadow: 0px 5px 25px -2px rgba(0, 0, 0, 0.03);
}
 .services-wrap .services .icon {
     margin-bottom: 20px;
     width: 64px;
     height: 64px;
     border-radius: 50%;
     background: #e3ecfe;
     position: relative;
     margin-left: 0;
}
 .services-wrap .services .icon span {
     position: absolute;
     font-size: 40px;
     top: 50%;
     left: 50%;
     transform: translate(-50%, -50%);
}
 .services-wrap .services .text h2 {
     font-size: 20px;
     font-weight: 500;
}
/* The .services block itself is used too */
 .services {
     width: 100%;
     background: #fff;
     padding: 30px;
     margin-bottom: 20px;
     transition: all 0.3s ease;
}
 .services .icon {
     margin: 0 auto;
}
 .services .icon span {
     font-size: 60px;
     line-height: 1.2;
     color: #8f4ff9;
}
 .services .text {
     color: #69666c;
     width: 100%;
}
 .services .text h2 {
     font-size: 26px;
     font-weight: 500;
     margin-bottom: 15px;
}
 .services:hover, .services.active {
     background: #8f4ff9;
     box-shadow: 0px 5px 25px -2px rgba(0, 0, 0, 0.18);
}
 .services:hover .icon, .services.active .icon {
     background: #9568fa;
}
 .services:hover .icon span, .services.active .icon span {
     color: #fff;
}
 .services:hover .text, .services.active .text {
     color: rgba(255, 255, 255, 0.9);
}
 .services:hover .text h2, .services.active .text h2 {
     color: #fff;
}
/* Footer */
 .ppgx-footer {
     padding: 3em 0 0 0;
     position: relative;
     z-index: 0;
     color: rgba(255, 255, 255, 0.9);
}
 .ppgx-footer .overlay {
     position: absolute;
     top: 0;
     left: 0;
     right: 0;
     bottom: 0;
     opacity: .8;
     background: #000000;
     z-index: -1;
}
 .ppgx-footer .ppgx-footer-widget h2 {
     color: #fff;
     margin-bottom: 40px;
     font-size: 18px;
     font-weight: 500;
}
 .sticky-top {
     position: -webkit-sticky;
     position: sticky;
     top: 0;
     z-index: 1020;
}


/* on hover (and when the card has .active like your template) */
.services:hover .icon .bi,
.services.active .icon .bi {
  color: #fff;
}
.services .icon {
  position: relative; /* needed for absolute centring */
}

.services .icon i {
  position: absolute;
  left: 50%;
  top: 50%;
  transform: translate(-50%, -50%);
  font-size: 2.8rem;
}

.form-check-input:checked {
    background-color: #8b48fa;
    border-color: #7f42e4;
}

.text-justify {
    text-align: justify;
}

/* Curated interaction summary text */
#interaction-summary {
  text-align: justify;
  line-height: 1.5;
  color: var(--bs-gray-600);
}

#evidence-table {
    font-size: 0.9rem;
    line-height: 1.3;
}

#evidence-table tr.ref-highlight {
  background-color: rgba(121, 13, 253, 0.095);
  transition: background-color 0.6s ease;
}

#evidence-table tr.ref-highlight.fade-out {
  background-color: transparent;
}

#evidence-table tbody tr.evidence-row {
  cursor: pointer;
}

#summaryModalBody .study-details {
    text-align: justify;
    line-height: 1.4;
}

#ddi-list li,
#proteine-block {
    line-height: 1.4;
}


.ref-link {
  cursor: pointer;
  user-select: none;
}

.ref-link:hover {
  color: #0d6efd;
  text-decoration: underline;
}

.adr-pill {
  font-size: 0.7em;
  line-height: 0.9
}

.custom-tooltip {
  --bs-tooltip-bg: var(--bd-violet-bg);
  --bs-tooltip-color: var(--bs-white);
}

.target-block,
.transporter-block {
    margin-top: 3px;
    margin-bottom: 3px;
}

.text-purple {
    color: #8f4ff9 !important;
}

.table-tight td, .table-tight th, .table-tight thead tr th { 
    padding-top: 0.25rem; 
    padding-bottom: 0.25rem; 
    line-height: 1.5; 
}

.table-tighter td, .table-tighter th, .table-tighter thead tr th  { 
    padding-top: 0.15rem; 
    padding-bottom: 0.15rem; 
    line-height: 1.3; 
}
